The main ingredient of filler injections is Hyaluronic acid, which can also be found in our body. Filler injection is an application based on the substitution of this substance which decreases with time. It prevents wrinkles and makes the skin look full and youthful. As for your question; You can see the effect immediately after the operation. In filling applications, the permanence varies between 6 and 12 months depending on the person and the applied area.